Leal-Egaña GroupPublications

Monavari M., Sohrabi R., Motasadizadeh H., Monavari M., Fatahi Y., Ejarestaghi Negin M., Fuentes-Chandia M., Leal-Egaña Aldo, Akrami M., Homaeigohar S.

"Levofloxacin loaded poly (ethylene oxide)-chitosan/quercetin loaded poly (D,L-lactide-co-glycolide) core-shell electrospun nanofibers for burn wound healing"

Frontiers in Bioengineering and Biotechnology, Vol. 12; 2024 

Antonelli Y., Krüger R., Buehler A., Monavari M., Fuentes-Chandía M., Colombo F., Palmisano R., Boßerhoff A.K, Kappelmann-Fenzl M., Schödel J., Boccaccini A.R., Selhuber-Unkel C., Letort G., Leal-Egaña A. 

"When Mechanical Stress Matters: Generation of Polyploid Giant Cancer Cells in Tumor-Like Microcapsules." 

Adv. Funct. Mater. 2024, 2311139.

V Ramesh, PN Gollavilli, L Pinna, MA Siddiqui, A Martinez Turtos, F Napoli, Y Antonelli, A Leal-Egaña, JF Havelund, ST Jakobsen, E Le Boiteux, M Volante, NJ Færgeman, ON Jensen, R Siersbæk, K Somyajit, P Ceppi

“Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma”

EMBO Molecular Medicine, Vol. 15, Issue 12, e17836; 2023

Taale, M.; Schamberger, B.; Taheri, F.; Antonelli, Y.; Leal-Egana, A.; Selhuber-Unkel, C. 

"In situ fabrication of constraints for multicellular microspheroids using two photon lithography"

Adv. Funct. Mater. 2024, 34, 2302356 (first published in July 2023)

S. Stagnoli, C. Garro, O. Ertekin, S. Heid, S. Seyferth, G. Soria, N. Mariano Correa, A. Leal-Egaña, A. R. Boccaccini

Topical systems for the controlled release of antineoplastic Drugs: Oxidized Alginate-Gelatin Hydrogel/Unilamellar vesicles

Journal of Colloid and Interface Science, Vol. 629, p. 1066-1080; 2023

Aldo Leal-Egana, Aldo Roberto Boccaccini

“3d-1d multidimensional cancer-on-a-chip”

Patent; 2022

Ö. Ertekin, M. Monavari, R. Krüger, M. Fuentes-Chandía, B. Parma, G. Letort, P. Tripal, A. Boccaccinial, A. Bosserhoff, P. Ceppi, M. Kappelmann-Fenzl, A. Leal-Egaña

“3D Hydrogel-based microcapsules as an in vitro model to study tumorigenicity, cell migration and drug resistance”

Acta Biomaterialia, Vol. 141, p. 208-220; 2022

V. Bednarzig, E. Karakaya, A. Leal-Egaña, J. Teßmar, A. R. Boccaccini, R. Detsch

"Advanced ADA-GEL bioink for bioprinted artificial cancer models"

Bioprinting, Vol. 23, p. e00145; 2021

A. Aguilar-Rabiela, A. Leal-Egaña, Q. Nawaz, A. Boccaccini

“Integration of Mesoporous Bioactive Glass Nanoparticles and Curcumin into PHBV Microspheres as Biocompatible Composite for Drug Delivery Applications”

Molecules, Vol. 26-11, p. 3177; 2021

M. Fuentes‐Chandía, A. Vierling, M. Kappelmann‐Fenzl, M. Monavari, G. Letort, L. Höne, B. Parma, S. Khan Antara, Ö. Ertekin, R. Palmisano, M. Dong, K. Böpple, A. R. Boccaccini, P. Ceppi, A. K. Bosserhoff, A. Leal‐Egaña

“3D Spheroids Versus 3D Tumor‐Like Microcapsules: Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells”

Advanced Biology, Vol. 5-7, p. 2000349; 2021

Q. Nawaz, M. Fuentes-Chandia, V. Tharmalingam, M. A. Ur Rehman, A. Leal-Egana, A. R. Boccaccini

“Silibinin releasing mesoporous bioactive glass nanoparticles with potential for breast cancer therapy”

Ceramics International, Vol. 46, Issue 18, p. 29111-29119; 2020

Aldo Leal-Egaña, Martial Balland, Aldo R. Boccaccini

Re-Engineering Artificial Neoplastic Milieus: Taking Lessons from Mechano-and Topobiology

Trends in Biotechnology, Vol.38, Issue 2, p. 142-153; 2020

Nathalie Raffel, Ralf Dittrich, Tobias Bäuerle, Lisa Seyler, Amir Fattahi, Inge Hoffmann, Aldo Leal-Egaña, Matthias W Beckmann, Aldo R Boccaccini, Liliana Liverani

"Novel approach for the assessment of ovarian follicles infiltration in polymeric electrospun patterned scaffolds"

PLoS One, Vol. 14, Issue 4, p. e0215985; 2019

John G Hardy, Annabelle Bertin, Jose Guillermo Torres‐Rendon, Aldo Leal‐Egaña, Martin Humenik, Felix Bauer, Andreas Walther, Helmut Cölfen, Helmut Schlaad, Thomas R Scheibel

“Facile photochemical modification of silk protein–based biomaterials”

Macromolecular Bioscience, Vol. 18, Issue 11. p. 1800216; 2018

Mohammed Al-Jarsha, Vladimíra Moulisová, Aldo Leal-Egaña, Andrew Connell, Kurt B Naudi, Ashraf F Ayoub, Matthew J Dalby, Manuel Salmerón-Sánchez

"Engineered coatings for titanium implants to present ultralow doses of BMP-7"

ACS Biomaterials Science & Engineering, Vol. 4, Issue 5, p. 1812-1819; 2018

Aldo Leal-Egaña, Gaelle Letort, Jean-Louis Martiel, Andreas Christ, Timothée Vignaud, Caroline Roelants, Odile Filhol, Manuel Théry

“The size-speed-force relationship governs migratory cell response to tumorigenic factors”

Molecular Biology of the Cell, Vol. 28, Issue 12, p. 1612-1621; 2017

John G Hardy, Jose Guillermo Torres-Rendon, Aldo Leal-Egaña, Andreas Walther, Helmut Schlaad, Helmut Cölfen, Thomas R Scheibel

"Biomineralization of engineered spider silk protein-based composite materials for bone tissue engineering"

Materials, Vol. 9, Issue 7, p. 560; 2016

Jose Ballester-Beltran, Manus JP Biggs, Matthew J Dalby, Manuel Salmeron-Sanchez, Aldo Leal-Egana

“Sensing the difference: the influence of anisotropic cues on cell behavior”

Frontiers in Materials, Vol. 2, p. 29; 2015

Manuel Théry Jean-Louis Martiel, Aldo Leal, Laetitia Kurzawa, Martial Ballandx, Irene Wangx, Timotheé Vignaud, Qingzong Tseng

“Measurement of cell traction forces with ImageJ”

Methods Cell Biol, Vol. 125, p. 269-87; 2015

John G Hardy, André Pfaff, Aldo Leal‐Egaña, Axel HE Müller, Thomas R Scheibel

“Glycopolymer functionalization of engineered spider silk protein‐based materials for improved cell adhesion”

Macromolecular Bioscience, Vol. 14, Issue 7, p. 936-942; 2014

John G Hardy, Aldo Leal‐Egaña, Thomas R Scheibel

“Engineered Spider Silk Protein‐Based Composites for Drug Delivery”

Macromolecular Bioscience, Vol. 13, Issue 10, p. 1431-1437; 2013

Aldo Leal‐Egaña, Aránzazu Díaz‐Cuenca, Aldo R Boccaccini

“Tuning of cell–biomaterial anchorage for tissue regeneration”

Advanced Materials, Vol. 25, Issue 29, p. 4049-4057; 2013

Stefanie Wohlrab, Susanne Müller, Andreas Schmidt, Stefanie Neubauer, Horst Kessler, Aldo Leal-Egaña, Thomas Scheibel

“Cell adhesion and proliferation on RGD-modified recombinant spider silk proteins”

Biomaterials, Vol. 33, Issue 28, p. 6650-6659; 2012

Aldo Leal-Egaña, Anatol Fritsch, Felicia Heidebrecht, Aránzazu Díaz-Cuenca, Marcin Nowicki, Augustinus Bader, Josef Käs

“Tuning liver stiffness against tumours: an in vitro study using entrapped cells in tumour-like microcapsules”

Journal of the mechanical behavior of biomedical materials, Vol. 9, p. 113-121; 2012

Aldo Leal‐Egaña, Gregor Lang, Carolin Mauerer, Jasmin Wickinghoff, Michael Weber, Stefan Geimer, Thomas Scheibel

“Interactions of fibroblasts with different morphologies made of an engineered spider silk protein”

Advanced Engineering Materials, Vol. 14, Issue 3, p. B67-B75; 2012

Aldo Leal-Egana, Thomas Scheibel

“Interactions of cells with silk surfaces”

Journal of Materials Chemistry, Vol. 22, Issue 29, p. 14330-14336; 2012

Aldo Leal-Egaña, Ulf-Dietrich Braumann, Aránzazu Díaz-Cuenca, Marcin Nowicki, Augustinus Bader

“Determination of pore size distribution at the cell-hydrogel interface”

Journal of Nanobiotechnology, Vol. 9, p. 1-7; 2011

Aldo Leal‐Egaña, Thomas Scheibel

“Silk‐based materials for biomedical applications”

Biotechnology and Applied Biochemistry, Vol. 55, Issue 3, p. 155-167; 2010

Aldo Leal-Egaña, Aránzazu Díaz-Cuenca, Augustinus Bader

“Determination of the decay rate constant for hepatocytes immobilized in alginate microcapsules”

Journal of Microencapsulation, Vol. 27, Issue 1, p. 86-93; 2010

Aldo Leal-Egaña

“Multidisciplinary Teams: The Next Step in Science”

Journal of Technology Management & Innovation, Vol. 1, Issue 2, p. 21-26; 2006

Aldo Leal‐Egana, J Michael Heinrich, Mark D Smith, Marcin Nowicki, Augustinus Bader

“A simple non‐destructive method for the fixation and immunostaining of cultured cells encapsulated in alginate”

Biotechnology and Applied Biochemistry, Vol. 44, Issue 3, p. 143-150; 2006